PHT International is a US-headquarterted CRO, CDMO and fine chemicals trading / sourcing services organization with world-class manufacturing & laboratory facilities in China.

The services offered from our state-of-the-art CRO facility in Nantong, China include:

The full range of medicinal chemistry services include flexible FTE and FFS models
Analog Synthesis with specialist expertise in heterocyclic chemistry
Discovery and focused libraries
Scaffold Hopping
Impurity studies (elucidation, identification & synthesis)
Synthetic route scouting and selection
Scale-up from g to kg-scale demo batches (GLP)
Process development and optimization as required
Control of target crystal form and particle size distribution (PSD)
Comprehensive reports for fast and effective technology transfer to our CDMO site/to the customer's facilities

CDMO services offered from our cGMP/FDA inspected facility in Shangyu, China include:
A wide range of technologies to support small-molecule development and manufacturing, including high-pressure hydrogenation, high temperature & cryogenic chemistry and high-energy chemistries in flow (such as nitrations).
Projects can be supported from early-clinical phases through to full-scale commercial manufacturing (site capacity is >200m3)

In addition, PHT possesses proprietary technology to run surfactant-based chemical reactions using nanomicelles to reduce organic solvent waste and limit the amount of precious metals catalysts that are required.

Our dedicated sourcing group works with our trusted suppliers to provide customers with flexible and competitive options for a broad range of reagents, starting materials & intermediates. PHT offers a range of services including:

New Vendor selection & qualification
Sample qualification & registration​
Hazardous Material Expertise​
REACH, TSCA, and Other Regulatory Compliance​
On-site Supplier Audits​
Sustainable Sourcing ​options preferred wherever possible