Registration Opening Soon for BOS Events 2025!

Dates for BOS Events 2025 are confirmed as 11th and 12th June for BOS Basel 2025 and 25th and 26th November for BOS Manchester 2025. Please find further details outlining provisional floor plans and pricing options at the event links provided. Note that we plan to open for registrations on Monday 4th November at 09.00 GMT.

The focus of these events is partnerships in R&D outsourcing with the primary scope being development-stage CMC outsourcing of Small Molecules, Biologics and New Therapeutic Entities.

We continue to evaluate the opportunity for digital events and resources, please look out for an announcement soon on this. We look forward to welcoming you and your colleagues to BOS Events! Please contact the Bio2Business team for further details.

Featured Company (BOS Basel 2024)

Axplora
Axplora, created from the merger of Farmabios, Novasep and PharmaZell, is a leading API manufacturing partner to the world’s leading pharmaceutical and biotechnology companies, delivering top quality active ingredients on time and at scale, to the highest industry standards. Axplora is dedicated to...
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Featured Speaker (BOS Manchester 2024)

Process Development for the Manufacture of a Topical Pan-Trk Inhibitor Incorporating Decarboxylative Sp2-Sp3 Cross-Coupling.

Dr Neil Stevenson, CMC / Process Chemistry Manager, BenevolentAI

ABSTRACT: In collaboration between BenevolentAI and Concept Life Sciences, the development of a synthetic route towards topical pan-Trk inhibitor 1 is described. Process improvements include development of a decarboxylative sp2-sp3 cross-coupling as part of an eight-stage synthesis. This route has been reproducibly demonstrated in two GMP campaigns on multi-gram scale delivering API in >99% area purity by HPLC. The route design, process research, and manufacture has enabled crucial First-In-Human (FIH) clinical studies, through focus on speed of delivery. Click here to Read More